From around 1611 Shakespeare seems largely to have disengaged himself from the London theatre world and to have spent his time at his Stratford house, New Place. In March 1616 he signed his will, in which he left substantial property and other bequests to his family and friends, including theatre colleagues in the King's Men.

Shakespeare died in Stratford, aged fifty-two, on 23 April 1616, and was buried in Holy Trinity Church two days later. Within a short time a monument to him was put up, probably by his family, on the wall close to his grave. His widow, Anne, died in 1623 and was buried beside him. Shakespeare's family line came to an end with the death of his grand-daughter Elizabeth in 1670.